Accuracy of death certificate diagnosis of amyotrophic lateral sclerosis.

The reliability of death certificate reporting for amyotrophic lateral sclerosis.

INTRODUCTION THIS STUDY was designed to determine the usefulness of mortality statistics in estimating the prevalence of amyotrophic lateral sclerosis (ALS) by analysing the death certificates of a series of patients in whom this diagnosis had been made during life. Most of the descriptive epidemiologic information of ALS has been based primarily on the analysis of death certificate data [1, 21...

The diagnosis of amyotrophic lateral sclerosis.

The term Amyotrophic lateral sclerosis (ALS) covers a spectrum of neurodegenerative syndromes characterized by progressive degeneration of motor neurons (MNs). Other syndromes related to this spectrum of disorders include Progressive bulbar palsy (PBP), Progressive muscular atrophy (PMA), Primary lateral sclerosis (PLS), Flail arm syndrome (Vulpian-Bernhardt syndrome), Flail leg syndrome, and A...

Programmed cell death in amyotrophic lateral sclerosis.

Occurrence of amyotrophic lateral sclerosis among Iran-Iraq war veterans

  Abstract   Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurological   disorder with high mortality and morbidity. Some risk factors have been implicated for   ALS such as exposure to high magnetic fields, and trace elements like selenium, cadmium and lead. Afew studies have been carried out throughout the world to evaluate   the prevalence of ALS among veterans. This stud...

Unexpected death of a ventilator-dependent amyotrophic lateral sclerosis patient.

BACKGROUND Amyotrophic lateral sclerosis (ALS) is a fatal, progressive, neurodegenerative disease and most patients affected die of respiratory compromise and/or pneumonia within 2-3 years of diagnosis. As ALS progresses, ventilator assistance is required. In the end stages of the disease, patients suffer from respiratory failure and may become ventilator-dependent. Deaths due to malfunction of...